Phenotypes associated with this allele

• Allele Symbol: Tiam1^{Gt(CSJ260)Byg}
• Allele Name: gene trap CSJ260, BayGenomics
• Allele ID: MGI:3880733
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tiam1^Gt(CSJ260)Byg/Tiam1^Gt(CSJ260)Byg	involves: 129P2/OlaHsd	MGI:5439293

Genotype
MGI:5439293

hm1

• Allelic Composition: Tiam1^{Gt(CSJ260)Byg}/Tiam1^{Gt(CSJ260)Byg}
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal forebrain morphology ( J:188067 )

• at E10.5, 10% of embryos show a collapsed forebrain with neural tube closure defect

abnormal diencephalon morphology ( J:188067 )

• at E10.5, the rostral and ventricular regions are much smaller in mice with grossly normal brain morphology

anencephaly ( J:188067 )

• most mice show severe anencephaly where the exposed brain tissue is completely degenerated at E13.5

exencephaly ( J:188067 )

• in some mice at E13.5