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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dbr1Gt(YTA280)Byg
gene trap YTA280, BayGenomics
MGI:3880498
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dbr1Gt(YTA280)Byg/Dbr1Gt(YTA280)Byg involves: 129P2/OlaHsd MGI:5770146
ht2
 		Dbr1Gt(YTA280)Byg/Dbr1+ involves: 129P2/OlaHsd MGI:5770147


Genotype
MGI:5770146
hm1
Allelic
Composition		 Dbr1Gt(YTA280)Byg/Dbr1Gt(YTA280)Byg
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbr1Gt(YTA280)Byg mutation (0 available); any Dbr1 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:223318 )
• no live mice are produced from breeding heterozygotes




Genotype
MGI:5770147
ht2
Allelic
Composition		 Dbr1Gt(YTA280)Byg/Dbr1+
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbr1Gt(YTA280)Byg mutation (0 available); any Dbr1 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal class switch recombination ( J:223318 )
• in B cells
• however, somatic hypermutation in Peyers patches B cells is normal

immune system
abnormal class switch recombination ( J:223318 )
• in B cells
• however, somatic hypermutation in Peyers patches B cells is normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory