All Phenotypes Mcm7<Gt(YTA285)Byg> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mcm7^{Gt(YTA285)Byg}
gene trap YTA285, BayGenomics
MGI:3880493

Summary

5 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mcm7^{Gt(YTA285)Byg}/Mcm7^{Gt(YTA285)Byg}	involves: 129P2/OlaHsd * C3HeB/FeJ	MGI:4838134
ht2	Mcm7^{Gt(YTA285)Byg}/Mcm7⁺	involves: 129P2/OlaHsd * C3HeB/FeJ	MGI:4838136
cx3	Mcm2^{Gt(AB0178)Wtsi}/Mcm2⁺ Mcm3^{Gt(RRR002)Byg}/Mcm3⁺ Mcm6^{Gt(YHD248)Byg}/Mcm6⁺ Mcm7^{Gt(YTA285)Byg}/Mcm7⁺	involves: 129P2/OlaHsd * C3HeB/FeJ	MGI:4838124
cx4	Mcm2^{Gt(AB0178)Wtsi}/Mcm2⁺ Mcm3^{Gt(RRR002)Byg}/Mcm3⁺ Mcm4^{Gt(RRE056)Byg}/Mcm4⁺ Mcm6^{Gt(YHD248)Byg}/Mcm6⁺ Mcm7^{Gt(YTA285)Byg}/Mcm7⁺	involves: 129P2/OlaHsd * C3HeB/FeJ	MGI:4838137
cx5	Mcm4^chaos3/Mcm4^chaos3 Mcm7^{Gt(YTA285)Byg}/Mcm7⁺	involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J	MGI:4838117

Allelic Composition	Mcm7^{Gt(YTA285)Byg}/Mcm7^{Gt(YTA285)Byg}
Genetic Background	involves: 129P2/OlaHsd * C3HeB/FeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm7^{Gt(YTA285)Byg} mutation (0 available); any Mcm7 mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:165667 )

• no viable mice are present at birth

Allelic Composition	Mcm7^{Gt(YTA285)Byg}/Mcm7⁺
Genetic Background	involves: 129P2/OlaHsd * C3HeB/FeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm7^{Gt(YTA285)Byg} mutation (0 available); any Mcm7 mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

chromosomal instability ( J:165667 )

• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system

abnormal erythrocyte morphology ( J:165667 )

• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

Allelic Composition	Mcm2^{Gt(AB0178)Wtsi}/Mcm2⁺ Mcm3^{Gt(RRR002)Byg}/Mcm3⁺ Mcm6^{Gt(YHD248)Byg}/Mcm6⁺ Mcm7^{Gt(YTA285)Byg}/Mcm7⁺
Genetic Background	involves: 129P2/OlaHsd * C3HeB/FeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm2^{Gt(AB0178)Wtsi} mutation (0 available); any Mcm2 mutation (53 available)
Mcm3^{Gt(RRR002)Byg} mutation (0 available); any Mcm3 mutation (41 available)
Mcm6^{Gt(YHD248)Byg} mutation (0 available); any Mcm6 mutation (38 available)
Mcm7^{Gt(YTA285)Byg} mutation (0 available); any Mcm7 mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

chromosomal instability ( J:165667 )

• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system

abnormal erythrocyte morphology ( J:165667 )

• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

Allelic Composition	Mcm2^{Gt(AB0178)Wtsi}/Mcm2⁺ Mcm3^{Gt(RRR002)Byg}/Mcm3⁺ Mcm4^{Gt(RRE056)Byg}/Mcm4⁺ Mcm6^{Gt(YHD248)Byg}/Mcm6⁺ Mcm7^{Gt(YTA285)Byg}/Mcm7⁺
Genetic Background	involves: 129P2/OlaHsd * C3HeB/FeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm2^{Gt(AB0178)Wtsi} mutation (0 available); any Mcm2 mutation (53 available)
Mcm3^{Gt(RRR002)Byg} mutation (0 available); any Mcm3 mutation (41 available)
Mcm4^{Gt(RRE056)Byg} mutation (0 available); any Mcm4 mutation (43 available)
Mcm6^{Gt(YHD248)Byg} mutation (0 available); any Mcm6 mutation (38 available)
Mcm7^{Gt(YTA285)Byg} mutation (0 available); any Mcm7 mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

chromosomal instability ( J:165667 )

• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system

abnormal erythrocyte morphology ( J:165667 )

• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

Allelic Composition	Mcm4^chaos3/Mcm4^chaos3 Mcm7^{Gt(YTA285)Byg}/Mcm7⁺
Genetic Background	involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm4^chaos3 mutation (1 available); any Mcm4 mutation (43 available)
Mcm7^{Gt(YTA285)Byg} mutation (0 available); any Mcm7 mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:165667 )

• only 8% of expected mice survive to weaning

prenatal lethality, incomplete penetrance ( J:165667 )

• 50% of expected mice are liveborn

hematopoietic system

abnormal erythrocyte morphology ( J:165667 )

• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with Mcm4^chaos3 homozygotes

reticulocytosis ( J:165667 )

• mice exhibit an increase in the number of CD71+ (proliferating cells, reticulocytes, erythroid precursors) cells compared with Mcm4^chaos3 homozygotes

cellular

chromosomal instability ( J:165667 )

• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with Mcm4^chaos3 homozygotes

growth/size/body

decreased body weight ( J:165667 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24