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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Osbpl8Gt(DD0748)Wtsi
gene trap DD0748, Wellcome Trust Sanger Institute
MGI:3871235
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Osbpl8Gt(DD0748)Wtsi/Osbpl8Gt(DD0748)Wtsi B6.129P2-Osbpl8Gt(DD0748)Wtsi MGI:5514254


Genotype
MGI:5514254
hm1
Allelic
Composition
Osbpl8Gt(DD0748)Wtsi/Osbpl8Gt(DD0748)Wtsi
Genetic
Background
B6.129P2-Osbpl8Gt(DD0748)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Osbpl8Gt(DD0748)Wtsi mutation (0 available); any Osbpl8 mutation (64 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• total and free cholesterol starting at 13 weeks in female and male mice
• total and free cholesterol after 5 weeks on a chow diet in male mice
• total and free cholesterol after 5 weeks on a Western diet in male and female mice
• starting at 13 weeks in female and male mice
• after 5 weeks on a Western diet in male and female mice
• in female, but not male, mice at 13 weeks and after 5 weeks on a chow diet
• in male, but not female mice, after 5 weeks on a Western diet
• increased serum apoprotein A-I at 13 weeks in female and male mice
• increased serum apoprotein A-I after 5 weeks on a chow diet in female mice
• however, mice fed a Western diet exhibit normal apoprotein A-I serum levels
• increased in male, but not female, mice fed a chow diet





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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory