All Phenotypes Wwp2<Gt(HMA140)Byg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Wwp2^{Gt(HMA140)Byg}
gene trap HMA140, BayGenomics
MGI:3868073

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Wwp2^{Gt(HMA140)Byg}/Wwp2^{Gt(HMA140)Byg}	B6.129P2-Wwp2^{Gt(HMA140)Byg}	MGI:5774708
ht2	Wwp2^{Gt(HMA140)Byg}/Wwp2^em1Asah	involves: 129P2/OlaHsd * C57BL/6J * DBA	MGI:6359837
cx3	Mir140^em1Asah/Mir140⁺ Wwp2^{Gt(HMA140)Byg}/Wwp2⁺	involves: 129P2/OlaHsd * C57BL/6J * DBA	MGI:6359840

Allelic Composition	Wwp2^{Gt(HMA140)Byg}/Wwp2^{Gt(HMA140)Byg}
Genetic Background	B6.129P2-Wwp2^{Gt(HMA140)Byg}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wwp2^{Gt(HMA140)Byg} mutation (0 available); any Wwp2 mutation (373 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal jaw morphology ( J:228709 )

• misaligned in some mice

long lower incisors ( J:228709 )

• overgrowth of mandibular incisors

short nasal bone ( J:228709 )

domed cranium ( J:228709 )

• in all mice to varying severity

abnormal snout morphology ( J:228709 )

• twisted in some mice

short snout ( J:228709 )

• in all mice to varying severity

growth/size/body

long lower incisors ( J:228709 )

• overgrowth of mandibular incisors

short nasal bone ( J:228709 )

abnormal snout morphology ( J:228709 )

• twisted in some mice

short snout ( J:228709 )

• in all mice to varying severity

decreased body size ( J:228709 )

skeleton

abnormal jaw morphology ( J:228709 )

• misaligned in some mice

long lower incisors ( J:228709 )

• overgrowth of mandibular incisors

short nasal bone ( J:228709 )

domed cranium ( J:228709 )

• in all mice to varying severity

respiratory system

short nasal bone ( J:228709 )

Allelic Composition	Wwp2^{Gt(HMA140)Byg}/Wwp2^em1Asah
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wwp2^em1Asah mutation (0 available); any Wwp2 mutation (373 available)
Wwp2^{Gt(HMA140)Byg} mutation (0 available); any Wwp2 mutation (373 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

craniofacial phenotype ( J:278573 )

Allelic Composition	Mir140^em1Asah/Mir140⁺ Wwp2^{Gt(HMA140)Byg}/Wwp2⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir140^em1Asah mutation (0 available); any Mir140 mutation (1 available)
Wwp2^{Gt(HMA140)Byg} mutation (0 available); any Wwp2 mutation (373 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

decreased cranium height ( J:278573 )

skeleton

decreased cranium height ( J:278573 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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