Phenotypes associated with this allele

• Allele Symbol: Tbc1d23^{Gt(BA0556)Wtsi}
• Allele Name: gene trap BA0556, Wellcome Trust Sanger Institute
• Allele ID: MGI:3857844
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tbc1d23^Gt(BA0556)Wtsi/Tbc1d23^Gt(BA0556)Wtsi	B6.129P2-Tbc1d23^Gt(BA0556)Wtsi	MGI:5316042

Genotype
MGI:5316042

hm1

• Allelic Composition: Tbc1d23^{Gt(BA0556)Wtsi}/Tbc1d23^{Gt(BA0556)Wtsi}
• Genetic Background: B6.129P2-Tbc1d23^{Gt(BA0556)Wtsi}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased circulating interleukin-6 level ( J:181861 )

• elevated 6 hours after intra peritoneal injection of lipopolysaccharide

abnormal tumor necrosis factor level ( J:181861 )

• levels in macrophage start to increase 1-2 hours after lipopolysaccharide injection but not before

increased circulating tumor necrosis factor level ( J:181861 )

• elevated 6 hours after intra peritoneal injection of lipopolysaccharide

increased inflammatory response ( J:181861 )

• increased number of inflammatory cells in the peritoneum 6 hours after intra peritoneal injection of lipopolysaccharide

homeostasis/metabolism

increased circulating interleukin-6 level ( J:181861 )

• elevated 6 hours after intra peritoneal injection of lipopolysaccharide

abnormal tumor necrosis factor level ( J:181861 )

• levels in macrophage start to increase 1-2 hours after lipopolysaccharide injection but not before

increased circulating tumor necrosis factor level ( J:181861 )

• elevated 6 hours after intra peritoneal injection of lipopolysaccharide