Phenotypes associated with this allele

• Allele Symbol: Arf4^{Gt(AY0614)Wtsi}
• Allele Name: gene trap AY0614, Wellcome Trust Sanger Institute
• Allele ID: MGI:3857506
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arf4^Gt(AY0614)Wtsi/Arf4^Gt(AY0614)Wtsi	involves: 129P2/OlaHsd * C57BL/6	MGI:5605371

Genotype
MGI:5605371

hm1

• Allelic Composition: Arf4^{Gt(AY0614)Wtsi}/Arf4^{Gt(AY0614)Wtsi}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:215153 )

• no live embryos after E10.5

growth/size/body

decreased embryo size ( J:215153 )

• smaller than controls at E9.5

embryo

embryo phenotype ( J:215153 )

N • nodal cilia are functional

incomplete embryo turning ( J:215153 )

• almost never complete

decreased embryo size ( J:215153 )

• smaller than controls at E9.5

abnormal visceral endoderm morphology ( J:215153 )

• poorly organized microvilli and apical vacuoles are missing

• bulbous misshapen microvilli frequently observed with small vescicles

• reduced cell-cell contacts