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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Atrtm1Twgl
targeted mutation 1, Thomas W Glover
MGI:3851820
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Atrtm1Twgl/Atrtm1Twgl involves: 129S6/SvEvTac * C57BL/6J MGI:3851909
ht2
Atrtm1Twgl/Atr+ involves: 129S6/SvEvTac * C57BL/6J MGI:3851908


Genotype
MGI:3851909
hm1
Allelic
Composition
Atrtm1Twgl/Atrtm1Twgl
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atrtm1Twgl mutation (0 available); any Atr mutation (132 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• in fibroblasts following treatment with APH
• fibroblasts treated with 0.4 uM APH exhibit increased chromosomal gaps and breaks compared with similarly treated wild-type cells
• treatment with 0.4 uM APH induces increased chromosomal breakage at common fragile sites compared to in wild-type cells




Genotype
MGI:3851908
ht2
Allelic
Composition
Atrtm1Twgl/Atr+
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atrtm1Twgl mutation (0 available); any Atr mutation (132 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• in fibroblasts following treatment with APH
• fibroblasts treated with 0.4 uM APH exhibit increased chromosomal gaps and breaks compared with similarly treated wild-type cells but not as much as in homozygous cells





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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory