Analysis Tools
cardiovascular system
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• after induced ischemia-reperfusion (I-R) injury, mice show significant protection compared to wild-type controls as indicated by reduced viable myocardium area at risk (AAR) versus nonviable infarcted area (IA)
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• significantly less cleavage of caspase-3 (reduced by about 50%) is observed compared to wild-type
• significant reduction in DNA laddering after I-R injury compared to wild-type
• total apoptosis rate in left ventricle infarcted area is reduced leading to a decrease in the index of cell death
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muscle
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• after induced ischemia-reperfusion (I-R) injury, mice show significant protection compared to wild-type controls as indicated by reduced viable myocardium area at risk (AAR) versus nonviable infarcted area (IA)
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• significantly less cleavage of caspase-3 (reduced by about 50%) is observed compared to wild-type
• significant reduction in DNA laddering after I-R injury compared to wild-type
• total apoptosis rate in left ventricle infarcted area is reduced leading to a decrease in the index of cell death
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cellular
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• significantly less cleavage of caspase-3 (reduced by about 50%) is observed compared to wild-type
• significant reduction in DNA laddering after I-R injury compared to wild-type
• total apoptosis rate in left ventricle infarcted area is reduced leading to a decrease in the index of cell death
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