About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Arb2a+
wild type
MGI:3851552
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Arb2aTg(Tyr)TpNpln/Arb2a+ involves: FVB/N MGI:7429208
cx2
 		Chd7Gt(S20-7E1)Sor/Chd7+
Arb2aTg(Tyr)TpNpln/Arb2a+ 		involves: 129S4/SvJaeSor * C57BL/6 * FVB/N MGI:7429212


Genotype
MGI:7429208
ht1
Allelic
Composition		 Arb2aTg(Tyr)TpNpln/Arb2a+
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arb2aTg(Tyr)TpNpln mutation (0 available); any Arb2a mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
head spot ( J:260599 )
• white spot is seen on the head

pigmentation
head spot ( J:260599 )
• white spot is seen on the head




Genotype
MGI:7429212
cx2
Allelic
Composition		 Chd7Gt(S20-7E1)Sor/Chd7+
Arb2aTg(Tyr)TpNpln/Arb2a+
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arb2aTg(Tyr)TpNpln mutation (0 available); any Arb2a mutation (29 available)
Chd7Gt(S20-7E1)Sor mutation (1 available); any Chd7 mutation (134 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:260599 )
• mice exhibit a higher frequency of premature postnatal death
prenatal lethality, incomplete penetrance ( J:260599 )
• lower than expected number of mice at birth

growth/size/body
decreased body size ( J:260599 )
• mice are smaller at weaning age than wild-type mice or either single heterozygote

behavior/neurological

reproductive system
sex reversal ( J:260599 )
• mice exhibit a higher frequency of male-to-female sex reversal

vision/eye
abnormal optic fissure closure ( J:260599 )
• E12.5 eyes show a wider choroidal fissure than in either single heterozygote
retina coloboma ( J:260599 )
• coloboma is much more severe than in single heterozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory