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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kdrtm2Sato
targeted mutation 2, Thomas N Sato
MGI:3850417
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Kdrtm2Sato/Kdrtm2Sato
Vegfatm2Gne/Vegfatm2Gne
Tg(Pax6-cre,GFP)2Pgr/0 		involves: 129S1/Sv MGI:5705505
cn2
 		Kdrtm1Jrt/Kdrtm2Sato
Tg(Nes-cre)1Wmz/0 		involves: 129S1/Sv * 129X1/SvJ MGI:5432161


Genotype
MGI:5705505
cn1
Allelic
Composition		 Kdrtm2Sato/Kdrtm2Sato
Vegfatm2Gne/Vegfatm2Gne
Tg(Pax6-cre,GFP)2Pgr/0
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdrtm2Sato mutation (1 available); any Kdr mutation (72 available)
Tg(Pax6-cre,GFP)2Pgr mutation (0 available)
Vegfatm2Gne mutation (2 available); any Vegfa mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal retina vasculature morphology ( J:217533 )
• some arteriovenous crossings is observed
• however, mice do not exhibit early vertical vascular branching in the retina observed in Kdrtm2.1Jrt/Kdrtm2.1Jrt Tg(Pax6-cre,GFP)2Pgr mice

vision/eye
abnormal retina vasculature morphology ( J:217533 )
• some arteriovenous crossings is observed
• however, mice do not exhibit early vertical vascular branching in the retina observed in Kdrtm2.1Jrt/Kdrtm2.1Jrt Tg(Pax6-cre,GFP)2Pgr mice




Genotype
MGI:5432161
cn2
Allelic
Composition		 Kdrtm1Jrt/Kdrtm2Sato
Tg(Nes-cre)1Wmz/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdrtm1Jrt mutation (1 available); any Kdr mutation (72 available)
Kdrtm2Sato mutation (1 available); any Kdr mutation (72 available)
Tg(Nes-cre)1Wmz mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:175836 )
N
• normal numbers of gonadotropin-releasing hormone neurons




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory