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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tpcn2Gt(YHD437)Byg
gene trap YHD437, BayGenomics
MGI:3848998
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tpcn2Gt(YHD437)Byg/Tpcn2Gt(YHD437)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:3849000


Genotype
MGI:3849000
hm1
Allelic
Composition		 Tpcn2Gt(YHD437)Byg/Tpcn2Gt(YHD437)Byg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tpcn2Gt(YHD437)Byg mutation (1 available); any Tpcn2 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal pancreatic beta cell physiology ( J:149472 )
• NAADP (nicotinic acid adenine dinucleotide phosphate) fails to activate calcium ion currents in beta cell unlike in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory