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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Lama2dy-8J
dystrophia muscularis 8 Jackson
MGI:3848931
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Lama2dy-8J/Lama2dy-8J C57BL/6J-Lama2dy-8J/GrsrJ MGI:3848948


Genotype
MGI:3848948
hm1
Allelic
Composition
Lama2dy-8J/Lama2dy-8J
Genetic
Background
C57BL/6J-Lama2dy-8J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lama2dy-8J mutation (0 available); any Lama2 mutation (177 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• homozygotes usually die by 3 to 4 weeks of age

behavior/neurological
• hind limb paralysis is first noticeable by approximately 2 weeks of age

hearing/vestibular/ear
• in 2 homozygotes tested an increased ABR thresheld is found at the highest decibel intensity

muscle

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
congenital merosin-deficient muscular dystrophy 1A DOID:0110636 OMIM:607855
J:149729





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory