About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aqp4tm1.1Tsna
targeted mutation 1.1, Tsutomu Nakada
MGI:3848919
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Aqp4tm1.1Tsna/Aqp4tm1.1Tsna involves: C57BL/6 * CBA MGI:3848923


Genotype
MGI:3848923
hm1
Allelic
Composition		 Aqp4tm1.1Tsna/Aqp4tm1.1Tsna
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp4tm1.1Tsna mutation (1 available); any Aqp4 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal glial cell physiology ( J:149545 )
• activity-dependent glial swelling is impaired compared to in wild-type mice as indicated by infrared light scattering

cellular
abnormal glial cell physiology ( J:149545 )
• activity-dependent glial swelling is impaired compared to in wild-type mice as indicated by infrared light scattering




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory