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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aqp4tm1.1Tsna
targeted mutation 1.1, Tsutomu Nakada
MGI:3848919
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Aqp4tm1.1Tsna/Aqp4tm1.1Tsna involves: C57BL/6 * CBA MGI:3848923


Genotype
MGI:3848923
hm1
Allelic
Composition		 Aqp4tm1.1Tsna/Aqp4tm1.1Tsna
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp4tm1.1Tsna mutation (1 available); any Aqp4 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal glial cell physiology ( J:149545 )
• activity-dependent glial swelling is impaired compared to in wild-type mice as indicated by infrared light scattering

cellular
abnormal glial cell physiology ( J:149545 )
• activity-dependent glial swelling is impaired compared to in wild-type mice as indicated by infrared light scattering




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory