Phenotypes associated with this allele

• Allele Symbol: Tg(Myh6-PROKR1)13Cagn
• Allele Name: transgene insertion 13, Canan G Nebigil
• Allele ID: MGI:3848193
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Myh6-PROKR1)13Cagn/0	involves: C57BL/6 * CD-1 * DBA/2	MGI:3848215

Genotype
MGI:3848215

tg1

• Allelic Composition: Tg(Myh6-PROKR1)13Cagn/0
• Genetic Background: involves: C57BL/6 * CD-1 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal arteriole morphology ( J:149020 )

• mice exhibit an increase in coronary arterioles compared with wild-type mice

abnormal vascular development ( J:149020 )

• capillary formation in the heart is increased compared to in wild-type mice

abnormal heart morphology ( J:149020 )

• the extracellular matrix of the heart is increased and filled with capillary vessels compared to in wild-type mice

abnormal cardiovascular system physiology ( J:149020 )

• proliferation of cells at the epicardial-subepicardial area is increased compared to in wild-type mice

abnormal cardiac muscle contractility ( J:149020 )

• following treatment with isoproterenol, mice exhibit improved myocardial contractile function compared to similarly treated wild-type mice

muscle

abnormal cardiac muscle contractility ( J:149020 )

• following treatment with isoproterenol, mice exhibit improved myocardial contractile function compared to similarly treated wild-type mice