Phenotypes associated with this allele

• Allele Symbol: Tg(Vil1-Ascl2)1Cle
• Allele Name: transgene insertion 1, Hans Clevers
• Allele ID: MGI:3846679
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Vil1-Ascl2)1Cle/?	involves: C57BL/6 * CBA	MGI:3846693

Genotype
MGI:3846693

tg1

• Allelic Composition: Tg(Vil1-Ascl2)1Cle/?
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

abnormal ileum crypts of Lieberkuhn morphology ( J:148715 )

• in the ileum of 2 week old mice, crypts are elongated and hyperplastic

abnormal small intestinal villus morphology ( J:148715 )

• in the duodenum of 2 week old mice, villi are branched and display crypt-like products

• in the ileum of 2 week old mice, villi are short and disorganized

• pockets of villi have aberrant proliferation

branched small intestinal villi ( J:148715 )

• in the duodenum of 2 week old mice

decreased small intestinal villus height ( J:148715 )

• in the ileum of 2 week old mice

endocrine/exocrine glands

abnormal ileum crypts of Lieberkuhn morphology ( J:148715 )

• in the ileum of 2 week old mice, crypts are elongated and hyperplastic