Phenotypes associated with this allele

• Allele Symbol: Dsg4^arm
• Allele Name: armadillo
• Allele ID: MGI:3846150
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dsg4^arm/Dsg4^arm	involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd	MGI:3846152

Genotype
MGI:3846152

hm1

• Allelic Composition: Dsg4^arm/Dsg4^arm
• Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:104190 )

• affected mice appear smaller than their normal littermates

homeostasis/metabolism

skin edema ( J:104190 )

• histologic examination reveals generalized epidermal edema

integument

skin edema ( J:104190 )

• histologic examination reveals generalized epidermal edema

brittle hair ( J:104190 )

• hair of homozygous mutant mice is abnormally prone to breakage; consequentially, the hair coat of homozygous mutant mice is very short, particularly on the extremities, i.e., ears, tail, muzzle and limbs to the hock or elbow, and on the ventrum

absent guard hair ( J:104190 )

• the dorsal fur looks more normal than that elsewhere, but appears to lack guard hairs

abnormal hair shaft morphology ( J:104190 )

• above the base of the hair follicle is an area that stains brightly orange/pink, suggesting premature cornification of the hair shaft and inner root sheath

abnormal hair follicle inner root sheath morphology ( J:104190 )

• above the base of the hair follicle is an area that stains brightly orange/pink, suggesting premature cornification of the hair shaft and inner root sheath

enlarged hair follicles ( J:104190 )

• the bases of affected hair follicles have an "onion bulb" appearance

absent vibrissae ( J:104190 )

reddish skin ( J:104190 )

• skin of affected mice may be slightly hyperemic or reddened