About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hvcn1Gt(RRN293)Byg
gene trap RRN293, BayGenomics
MGI:3843777
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hvcn1Gt(RRN293)Byg/Hvcn1Gt(RRN293)Byg B6.129P2-Hvcn1Gt(RRN293)Byg MGI:3843781


Genotype
MGI:3843781
hm1
Allelic
Composition		 Hvcn1Gt(RRN293)Byg/Hvcn1Gt(RRN293)Byg
Genetic
Background		 B6.129P2-Hvcn1Gt(RRN293)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hvcn1Gt(RRN293)Byg mutation (1 available); any Hvcn1 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal neutrophil physiology ( J:148032 )
• neutrophils lack voltage-gated proton currents unlike wild-type cells
abnormal macrophage physiology ( J:148032 )
• macrophages lack voltage-gated proton currents unlike wild-type cells

hematopoietic system
abnormal neutrophil physiology ( J:148032 )
• neutrophils lack voltage-gated proton currents unlike wild-type cells
abnormal macrophage physiology ( J:148032 )
• macrophages lack voltage-gated proton currents unlike wild-type cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory