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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Camk2a-UBB*)3413-1Fwvl
transgene insertion 3413-1, FW van Leeuwen
MGI:3843483
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Camk2a-UBB*)3413-1Fwvl/? C57BL/6-Tg(Camk2a-UBB*)3413-1Fwvl MGI:3843522


Genotype
MGI:3843522
tg1
Allelic
Composition
Tg(Camk2a-UBB*)3413-1Fwvl/?
Genetic
Background
C57BL/6-Tg(Camk2a-UBB*)3413-1Fwvl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Camk2a-UBB*)3413-1Fwvl mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• in a fear-conditioning paradigm, 9-month old mice exhibit significantly less freezing behavior on day 8 after training than wild-type littermates; however, cued-conditioning behavior is similar in transgenic and wild-type littermates
• 9-month old male mice exhibit poor performance in the Morris water maze task in probe trials done 1 week after training commenced; mice show no quadrant preference for the former location of the platform, in contrast to wild-type mice, and significantly larger distance to platform travel compared to wild-type





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory