About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aqp7tm1Nlsn
targeted mutation 1, Soren Nielsen
MGI:3841695
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Aqp7tm1Nlsn/Aqp7tm1Nlsn involves: 129S1/Sv * C57BL/6 MGI:3841696
hm2
 		Aqp7tm1Nlsn/Aqp7tm1Nlsn involves: 129S1/Sv * C57BL/6N MGI:3841697


Genotype
MGI:3841696
hm1
Allelic
Composition		 Aqp7tm1Nlsn/Aqp7tm1Nlsn
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp7tm1Nlsn mutation (0 available); any Aqp7 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased urine glycerol level ( J:147631 )
• severe decrease in urinary glycerol concentrations

renal/urinary system
decreased urine glycerol level ( J:147631 )
• severe decrease in urinary glycerol concentrations




Genotype
MGI:3841697
hm2
Allelic
Composition		 Aqp7tm1Nlsn/Aqp7tm1Nlsn
Genetic
Background		 involves: 129S1/Sv * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp7tm1Nlsn mutation (0 available); any Aqp7 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal sperm physiology ( J:145790 )
• exposure to BWW330 and quinine indicates that spermatozoa have faster water transport during both swelling and shrinking




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory