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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aqp7tm1Nlsn
targeted mutation 1, Soren Nielsen
MGI:3841695
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Aqp7tm1Nlsn/Aqp7tm1Nlsn involves: 129S1/Sv * C57BL/6 MGI:3841696
hm2
 		Aqp7tm1Nlsn/Aqp7tm1Nlsn involves: 129S1/Sv * C57BL/6N MGI:3841697


Genotype
MGI:3841696
hm1
Allelic
Composition		 Aqp7tm1Nlsn/Aqp7tm1Nlsn
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp7tm1Nlsn mutation (0 available); any Aqp7 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased urine glycerol level ( J:147631 )
• severe decrease in urinary glycerol concentrations

renal/urinary system
decreased urine glycerol level ( J:147631 )
• severe decrease in urinary glycerol concentrations




Genotype
MGI:3841697
hm2
Allelic
Composition		 Aqp7tm1Nlsn/Aqp7tm1Nlsn
Genetic
Background		 involves: 129S1/Sv * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp7tm1Nlsn mutation (0 available); any Aqp7 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal sperm physiology ( J:145790 )
• exposure to BWW330 and quinine indicates that spermatozoa have faster water transport during both swelling and shrinking




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory