All Phenotypes Tg(Drd1-EGFP)X60Gsat MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Drd1-EGFP)X60Gsat
transgene insertion X60, GENSAT Project at Rockefeller University
MGI:3840915

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ppp1r1b^tm5.1Pggd/Ppp1r1b^tm5.1Pggd Tg(Drd1-cre)EY262Gsat/0 Tg(Drd1-EGFP)X60Gsat/0	involves: C57BL/6 * FVB/N * FVB/NTac	MGI:4830459

Allelic Composition	Ppp1r1b^tm5.1Pggd/Ppp1r1b^tm5.1Pggd Tg(Drd1-cre)EY262Gsat/0 Tg(Drd1-EGFP)X60Gsat/0
Genetic Background	involves: C57BL/6 * FVB/N * FVB/NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp1r1b^tm5.1Pggd mutation (0 available); any Ppp1r1b mutation (18 available)
Tg(Drd1-cre)EY262Gsat mutation (2 available)
Tg(Drd1-EGFP)X60Gsat mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

reduced long-term potentiation ( J:163700 )

• loss of expression in striatopallidal and striatonigral neurons results in a reduced LTP at the corticostriatal synapses

behavior/neurological

impaired behavioral response to xenobiotic ( J:163700 )

• haloperidol-induced catalepsy is reduced

• L-DOPA-induced dyskinesia. is absent

impaired behavioral response to cocaine ( J:163700 )

decreased locomotor activity ( J:163700 )

• in an open-field test

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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