Phenotypes associated with this allele

• Allele Symbol: Grb10^tm1.1Fuis
• Allele Name: targeted mutation 1.1, Fumitoshi Ishino
• Allele ID: MGI:3839230
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Grb10^tm1.1Fuis/Grb10^+	involves: 129S/SvEv * C57BL/6J	MGI:3839236

Genotype
MGI:3839236

ht1

• Allelic Composition: Grb10^tm1.1Fuis/Grb10⁺
• Genetic Background: involves: 129S/SvEv * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

embryonic growth retardation ( J:146865 )

• from E12.5 when this allele is paternally inherited

decreased body weight ( J:146865 )

• when this allele is paternally inherited, weight is 60% of normal throughout the postnatal period to adult stage

• when this allele is paternally inherited, mice are 57% of wild-type weight at day 20

decreased fetal size ( J:146865 )

• 30% at term when this allele is paternally inherited

embryo

embryonic growth retardation ( J:146865 )

• from E12.5 when this allele is paternally inherited

small placenta ( J:146865 )

• when this allele is paternally inherited, placental growth retardation is slight and observed from E13.5 unlike in wild-type mice

decreased placenta weight ( J:146865 )

• 20% at term when this allele is paternally inherited