All Phenotypes Eri1<tm1.2Anse> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Eri1^tm1.2Anse
targeted mutation 1.2, K Mark Ansel
MGI:3838637

Summary

2 genotypes

Allelic Composition	Eri1^tm1.2Anse/Eri1^tm1.2Anse
Genetic Background	involves: BALB/cJ * C57BL/6 * ICR * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eri1^tm1.2Anse mutation (0 available); any Eri1 mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality ( J:146701 )

• Background Sensitivity: just over 10% of mice survive to weaning unlike on a more inbred background where less than 10% survive to weaning

Allelic Composition	Eri1^tm1.2Anse/Eri1^tm1.2Anse
Genetic Background	involves: BALB/cJ * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eri1^tm1.2Anse mutation (0 available); any Eri1 mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• although born in Mendelian ratios, less than 10% of mice survive to weaning with most mice dieing within the first 2 days after birth

• Background Sensitivity: just under 10% of mice survive to weaning unlike on an outbred background where more than 10% survive to weaning

growth/size/body

decreased body size ( J:146701 )

• throughout adulthood

decreased fetal size ( J:146701 )

• at E15.5

cellular

decreased cell proliferation ( J:146701 )

• mouse embryonic fibroblasts grow slower than wild-type cells after 6 to 9 passages

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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