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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cacng1tm1Rgg
targeted mutation 1, Ronald G Gregg
MGI:3838110
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cacng1tm1Rgg/Cacng1tm1Rgg involves: 129S7/SvEvBrd MGI:3838111
ht2
 		Cacng1tm1Rgg/Cacng1+ involves: 129S7/SvEvBrd MGI:3838112


Genotype
MGI:3838111
hm1
Allelic
Composition		 Cacng1tm1Rgg/Cacng1tm1Rgg
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacng1tm1Rgg mutation (0 available); any Cacng1 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal muscle electrophysiology ( J:146419 )
• in cultured myotubes there is a significant increase in the Ca2+ current density and the rate of pre-pulse inactivation is reduced




Genotype
MGI:3838112
ht2
Allelic
Composition		 Cacng1tm1Rgg/Cacng1+
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cacng1tm1Rgg mutation (0 available); any Cacng1 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal muscle electrophysiology ( J:146419 )
• in cultured myotubes there is a significant increase in the Ca2+ current density and the rate of pre-pulse inactivation is reduced




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory