Analysis Tools
behavior/neurological
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• under dark dark conditions, the amplitude of behavioral rhythms is greatly attenuated and the periodicity is weakened compared to in similarly treated wild-type mice
• under dark dark conditions, mice exhibit reduced activity during the active period compared to similarly treated wild-type mice
• however, mice exhibit normal behavioral activity when light cues are present and normal circadian changes in body temperature
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homeostasis/metabolism
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• under dark dark conditions, circadian rhythms of Star and corticosterone protein expression in the adrenal gland are abolished unlike in similarly treated wild-type mice
• under dark dark conditions, daily rhythms of plasma corticosterone levels are strongly attenuated unlike in similarly treated wild-type mice
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• under dark dark conditions, circadian rhythms of corticosterone expression in the adrenal gland are abolished unlike in simialrly treated wild-type mice
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• under dark dark conditions, daily rhythms of plasma corticosterone levels are strongly attenuated unlike in simialrly treated wild-type mice
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