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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(PER2*S662G)867Ljp
transgene insertion 867, Louis J Ptacek
MGI:3837437
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Csnk1dGt(TEA020)Byg/Csnk1d+
Tg(PER2*S662G)867Ljp/0 		involves: 129P2/OlaHsd * C57BL/6 MGI:3852105
cx2
 		Per2tm1Drw/Per2tm1Drw
Tg(PER2*S662G)867Ljp/0 		involves: C57BL/6 MGI:3852104
cx3
 		Tg(CSNK1D,-EGFP)#Yfu/0
Tg(PER2*S662G)867Ljp/0 		involves: C57BL/6 MGI:3852108
tg4
 		Tg(PER2*S662G)867Ljp/0 involves: C57BL/6 MGI:3852102


Genotype
MGI:3852105
cx1
Allelic
Composition		 Csnk1dGt(TEA020)Byg/Csnk1d+
Tg(PER2*S662G)867Ljp/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csnk1dGt(TEA020)Byg mutation (0 available); any Csnk1d mutation (15 available)
Tg(PER2*S662G)867Ljp mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:126404 )
• circadian period is shortened 1.5 hours compared to in wild-type mice




Genotype
MGI:3852104
cx2
Allelic
Composition		 Per2tm1Drw/Per2tm1Drw
Tg(PER2*S662G)867Ljp/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Per2tm1Drw mutation (2 available); any Per2 mutation (71 available)
Tg(PER2*S662G)867Ljp mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:126404 )
• circadian period is shortened 3.3 hours compared to in wild-type mice
• however, mice under LD10.5:10.5 conditions exhibit normal on-off activity patterns




Genotype
MGI:3852108
cx3
Allelic
Composition		 Tg(CSNK1D,-EGFP)#Yfu/0
Tg(PER2*S662G)867Ljp/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CSNK1D,-EGFP)#Yfu mutation (0 available)
Tg(PER2*S662G)867Ljp mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:126404 )
• circadian period is shortened 3.2 hours compared to in wild-type mice




Genotype
MGI:3852102
tg4
Allelic
Composition		 Tg(PER2*S662G)867Ljp/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(PER2*S662G)867Ljp mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
prolonged circadian behavior period ( J:126404 )
• circadian period is 0.7 hours longer than in wild-type mice

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
advanced sleep phase syndrome 1 DOID:0110011 OMIM:604348
 J:126404




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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory