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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ccdc157+
wild type
MGI:3837127
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Ccdc157em1Ymxi/Ccdc157+ C57BL/6-Ccdc157em1Ymxi MGI:7616777


Genotype
MGI:7616777
ht1
Allelic
Composition
Ccdc157em1Ymxi/Ccdc157+
Genetic
Background
C57BL/6-Ccdc157em1Ymxi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccdc157em1Ymxi mutation (0 available); any Ccdc157 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• sperm show higher rates of malformed heads
• percentage of normal headed sperm is increased after Huangjing Zanyu treatment
• decrease in sperm motility
• sperm motility is improved after Huangjing Zanyu treatment
• males exhibit delayed reproductive age by about 28-30 days; while wild-type males take 29 days before wild-type females give first births after cohabiting, heterozygous mutant males take on average 58 days before heterozygous or homozygous females give their first births
• male mice fed Huangjiug Zanyu, a traditional Chinese medication, from 4 to 5 weeks of age until the time when the cohabited females first give birth, take an average of 33 days to the first births after cohabiting with females compared to heterozygous controls that take an average of 58 days

cellular
• sperm show higher rates of malformed heads
• percentage of normal headed sperm is increased after Huangjing Zanyu treatment
• decrease in sperm motility
• sperm motility is improved after Huangjing Zanyu treatment

behavior/neurological
• females cohabiting with heterozygous males exhibit repeated offspring consumption and other aggressive parental behaviors, resulting in difficulties obtaining live litters





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory