Analysis Tools
reproductive system
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• Background Sensitivity: more severe than in mice on a mixed background
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Allele Symbol Allele Name Allele ID |
Phf13Gt(XB691)Byg gene trap XB691, BayGenomics MGI:3836461 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• Background Sensitivity: more severe than in mice on a mixed background
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• between E13.5 and E15.5
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• early
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• between E13.5 and E15.5
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• disorganized at 10 weeks
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• at 5 weeks
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• completely by 20 weeks
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• mice exhibit a break-down in spermatogenesis
• mice exhibit abnormal spatial distribution and impaired differentiation of spermatogonial stem cells compared with wild-type mice
• Background Sensitivity: less severe than in mice on a congenic C57BL/6 background
• however, mice exhibit normal numbers of gonocytes and Sertoli cells
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• at 5, 10 and 20 weeks
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• after 5 weeks, male mice exhibit reproductive defects and require a substantially prolonged period of time to impregnate female mice compared with wild-type mice
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• at 5, 10 and 20 weeks
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• disorganized at 10 weeks
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• at 5 weeks
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• completely by 20 weeks
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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