About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bxs6BXSB/MpJ
BXSB/MpJ
MGI:3836289
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Bxs6BXSB/MpJ/Bxs6BXSB/MpJ B10.BXSB-(D13Mit3-D13Mit78) MGI:3836734
hm2
 		Bxs6BXSB/MpJ/Bxs6BXSB/MpJ involves: BXSB/MpJ * C57BL/10ScSnOlaHsd MGI:3836614
cx3
 		Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
X/Yaa 		B10.BXSB-(D13Mit3-D13Mit78) Yaa MGI:3836730
cx4
 		Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
Gpab1C57BL/6J/? 		involves: BXSB/MpJ * C57BL/10ScSnOlaHsd MGI:3836615


Genotype
MGI:3836734
hm1
Allelic
Composition		 Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
Genetic
Background		 B10.BXSB-(D13Mit3-D13Mit78)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
autoimmune response ( J:145049 )
• increased levels of gp70 immune complex formation
increased autoantibody level ( J:145049 )
• increased gp70 autoimmune antibody titers




Genotype
MGI:3836614
hm2
Allelic
Composition		 Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
Genetic
Background		 involves: BXSB/MpJ * C57BL/10ScSnOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
autoimmune response ( J:145903 )
• increased levels of gp70 immune complex
increased autoantibody level ( J:145903 )
• increased titers of gp70 autoantibodies
glomerulonephritis ( J:145903 )
• increased glomerulonephritis severity

renal/urinary system
glomerulonephritis ( J:145903 )
• increased glomerulonephritis severity




Genotype
MGI:3836730
cx3
Allelic
Composition		 Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
X/Yaa
Genetic
Background		 B10.BXSB-(D13Mit3-D13Mit78) Yaa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bxs6BXSB/MpJ mutation (0 available); any Bxs6 mutation (0 available)
Yaa mutation (18 available); any Yaa mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
autoimmune response ( J:145049 )
• increased levels of gp70 immune complex formation
increased autoantibody level ( J:145049 )
• increased gp70 autoantibody titers
glomerulonephritis ( J:145049 )
• increased glomerulonephritis incidence and severity
• decreased survival

hematopoietic system

renal/urinary system
glomerulonephritis ( J:145049 )
• increased glomerulonephritis incidence and severity
• decreased survival

growth/size/body
enlarged spleen ( J:145049 )




Genotype
MGI:3836615
cx4
Allelic
Composition		 Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
Gpab1C57BL/6J/?
Genetic
Background		 involves: BXSB/MpJ * C57BL/10ScSnOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
autoimmune response ( J:145903 )
• increased levels of gp70 immune complex
increased autoantibody level ( J:145903 )
• increased titers of gp70 autoantibodies




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory