Phenotypes associated with this allele

• Allele Symbol: Etv2^{Gt(141.1H7)Cmhd}
• Allele Name: gene trap 141.1H7, Centre for Modeling Human Disease
• Allele ID: MGI:3830713
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Etv2^Gt(141.1H7)Cmhd/Etv2^Gt(141.1H7)Cmhd	involves: 129S1/Sv * 129X1/SvJ	MGI:3830726

Genotype
MGI:3830726

hm1

• Allelic Composition: Etv2^{Gt(141.1H7)Cmhd}/Etv2^{Gt(141.1H7)Cmhd}
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Absence of an endocardial/endothelial lineage in Etv2^{Gt(141.1H7)Cmhd}/Etv2^{Gt(141.1H7)Cmhd} heart and embryo

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:143866 )

• mice die between E9 and E10.5

cardiovascular system

abnormal vascular development ( J:143866 )

• at E8.5, mice lack vasculature such as the primary heart vein and the dorsal aorta

abnormal dorsal aorta morphology ( J:143866 )

• absent at E8.5

abnormal heart development ( J:143866 )

• at E8.5, mice lack endocardial/endothelial lineages in the heart and embryo

• however, this absence cannot be accounted for by increased apoptosis or decreased cell proliferation

absent heartbeat ( J:143866 )

• at E9.5 and E10.5

embryo

embryonic growth retardation ( J:143866 )

• between E9 and E10.5

abnormal embryonic tissue morphology ( J:143866 )

• at E8.5, mice lack endocardial/endothelial lineages in the heart and embryo

• however, this absence cannot be accounted for by increased apoptosis or decreased cell proliferation

growth/size/body

embryonic growth retardation ( J:143866 )

• between E9 and E10.5