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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lrp1tm2Ajmr
targeted mutation 2, Anton J M Roebroek
MGI:3830330
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lrp1tm2Ajmr/Lrp1tm2Ajmr involves: 129P2/OlaHsd * C57BL/6 MGI:3830349


Genotype
MGI:3830349
hm1
Allelic
Composition		 Lrp1tm2Ajmr/Lrp1tm2Ajmr
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp1tm2Ajmr mutation (1 available); any Lrp1 mutation (212 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
abnormal liver morphology ( J:144146 )
• adult livers exhibit vacuolization of von-Kupffer cells unlike wild-type livers




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory