Phenotypes associated with this allele

• Allele Symbol: Eppk1^tm1Safu
• Allele Name: targeted mutation 1, Sakuhei Fujiwara
• Allele ID: MGI:3830327
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eppk1^tm1Safu/Eppk1^tm1Safu	involves: 129 * C57BL/6J	MGI:3830329

Genotype
MGI:3830329

hm1

• Allelic Composition: Eppk1^tm1Safu/Eppk1^tm1Safu
• Genetic Background: involves: 129 * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

enhanced wound healing ( J:144147 )

• mice exhibit wound closure 1 to 2 days before wild-type mice

• mice exhibit decreased hypertrophy at the wound's edge and the leading edge extends a long distance compared to in wild-type mice

• epithelialization in an in vitro wound edge model is enhanced 1.2-fold compared to for wild-type cells

integument

increased keratinocyte migration ( J:144147 )

• keratinocyte migration as measured by epithelial outgrowth is increased 1.2-fold and 1.5-fold when mitosis is inhibited compared to for wild-type cells

cellular

increased keratinocyte migration ( J:144147 )

• keratinocyte migration as measured by epithelial outgrowth is increased 1.2-fold and 1.5-fold when mitosis is inhibited compared to for wild-type cells