All Phenotypes Tmprss6<m3Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tmprss6^m3Btlr
mutation 3, Bruce Beutler
MGI:3829007

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmprss6^m3Btlr/Tmprss6^m3Btlr	C57BL/6J-Tmprss6^m3Btlr	MGI:3829008

Allelic Composition	Tmprss6^m3Btlr/Tmprss6^m3Btlr
Genetic Background	C57BL/6J-Tmprss6^m3Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmprss6^m3Btlr mutation (0 available); any Tmprss6 mutation (46 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased circulating iron level ( J:143779 )

• corrected by dietary iron supplementation

reproductive system

reduced female fertility ( J:143779 )

• corrected by dietary iron supplementation

integument

alopecia ( J:143779 )

• homozygous mutant mice lose hair on their bodies, while that on their heads is unaffected

• corrected by dietary iron supplementation

sparse hair ( J:143779 )

• homozygous mutant mice lose hair on their bodies, while that on their heads is unaffected

• corrected by dietary iron supplementation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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