All Phenotypes Gt(ROSA)26Sor<tm3(Gli3)Amc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gt(ROSA)26Sor^tm3(Gli3)Amc
targeted mutation 3, Andrew P McMahon
MGI:3828280

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^tm3(Gli3)Amc/Gt(ROSA)26Sor⁺ Tg(Prrx1-cre)1Cjt/0	involves: 129 * C57BL/6J * CBA * SJL/J * Swiss Webster	MGI:3828285

Allelic Composition	Gt(ROSA)26Sor^tm3(Gli3)Amc/Gt(ROSA)26Sor⁺ Tg(Prrx1-cre)1Cjt/0
Genetic Background	involves: 129 * C57BL/6J * CBA * SJL/J * Swiss Webster

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm3(Gli3)Amc mutation (1 available); any Gt(ROSA)26Sor mutation (1046 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

polydactyly ( J:143454 )

• mice exhibit variable preaxial forelimb polydactyly

short limbs ( J:143454 )

• limb truncation

skeleton

decreased bone mineral density ( J:143454 )

• mice exhibit reduced mineralization

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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