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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sall1tm1Jkoh
targeted mutation 1, Jurgen Kohlhase
MGI:3828111
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Sall1tm1Jkoh/Sall1+
Sall4Gt(W097E01)Flo/Sall4+ 		involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ MGI:3828112
cx2
 		Sall1tm1Jkoh/Sall1tm1Jkoh
Sall4Gt(W097E01)Flo/Sall4+ 		involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ MGI:3828113


Genotype
MGI:3828112
cx1
Allelic
Composition		 Sall1tm1Jkoh/Sall1+
Sall4Gt(W097E01)Flo/Sall4+
Genetic
Background		 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sall1tm1Jkoh mutation (0 available); any Sall1 mutation (78 available)
Sall4Gt(W097E01)Flo mutation (0 available); any Sall4 mutation (145 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:143350 )
• only 4 of 79 offspring of heterozygous crosses were compound heterozygotes

nervous system
open neural tube ( J:143350 )
• partial penetrance of neural tube defects

embryo
open neural tube ( J:143350 )
• partial penetrance of neural tube defects




Genotype
MGI:3828113
cx2
Allelic
Composition		 Sall1tm1Jkoh/Sall1tm1Jkoh
Sall4Gt(W097E01)Flo/Sall4+
Genetic
Background		 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sall1tm1Jkoh mutation (0 available); any Sall1 mutation (78 available)
Sall4Gt(W097E01)Flo mutation (0 available); any Sall4 mutation (145 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo
embryonic growth retardation ( J:143350 )
• general growth retardation is seen at E10.5
open neural tube ( J:143350 )
• full penetrance of neural tube defects

nervous system
open neural tube ( J:143350 )
• full penetrance of neural tube defects

growth/size/body
embryonic growth retardation ( J:143350 )
• general growth retardation is seen at E10.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory