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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Arg1tm1.1Pmu
targeted mutation 1.1, Peter J Murray
MGI:3826848
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Arg1tm1.1Pmu/Arg1tm1.1Pmu involves: C57BL/6 * NZB MGI:3826859


Genotype
MGI:3826859
hm1
Allelic
Composition		 Arg1tm1.1Pmu/Arg1tm1.1Pmu
Genetic
Background		 involves: C57BL/6 * NZB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arg1tm1.1Pmu mutation (0 available); any Arg1 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality ( J:143229 )
• gross phenotype is stated to be identical to that of Arg1tm1Rki homozygotes; however, no data are provided

immune system
increased macrophage nitric oxide production ( J:143229 )
• macrophages produce more nitrous oxide in response to LPS stimulation or Mycobacterium bovis infection

homeostasis/metabolism
increased macrophage nitric oxide production ( J:143229 )
• macrophages produce more nitrous oxide in response to LPS stimulation or Mycobacterium bovis infection

hematopoietic system
increased macrophage nitric oxide production ( J:143229 )
• macrophages produce more nitrous oxide in response to LPS stimulation or Mycobacterium bovis infection




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory