Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shmt1tm1.1Stov mutation
(0 available);
any
Shmt1 mutation
(43 available)
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liver/biliary system
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• on a folate/choline deficient diet levels of S-adenosylmethionine are increased and levels of S-adenosylhomocysteine are decreased compared to wild-type mice on the same diet
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shmt1tm1.1Stov mutation
(0 available);
any
Shmt1 mutation
(43 available)
|
|
|
liver/biliary system
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• at 6 weeks of age, levels of S-adenosylmethionine are elevated 2 fold and levels of S-adenosylhomocysteine are decreased by 60%
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|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shmt1tm1.1Stov mutation
(0 available);
any
Shmt1 mutation
(43 available)
|
|
|
liver/biliary system
|
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• liver nuclear DNA shows increased uracil incorporation compared to wild-type and homozygous mutant mice
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Analysis Tools
