About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nrxn2tm3Sud
targeted mutation 3, Thomas C Sudhof
MGI:3820412
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nrxn2tm3Sud/Nrxn2tm3Sud involves: 129 * C57BL/6 MGI:3820420


Genotype
MGI:3820420
hm1
Allelic
Composition		 Nrxn2tm3Sud/Nrxn2tm3Sud
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrxn2tm3Sud mutation (0 available); any Nrxn2 mutation (91 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

growth/size/body
decreased body weight ( J:142107 )
• surviving mice display a 30-40% decrease in body weight compared to controls

nervous system
abnormal inhibitory postsynaptic currents ( J:142107 )
• in cortical slices IPSCs are decreased




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory