Analysis Tools
normal phenotype
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• while there was a decrease in GFP expression by thymocytes differentiating into CD4 + T cells, no phenotypic abnormalities are reported
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Allele Symbol Allele Name Allele ID |
Zbtb7btm2Itan targeted mutation 2, Ichiro Taniuchi MGI:3817518 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• while there was a decrease in GFP expression by thymocytes differentiating into CD4 + T cells, no phenotypic abnormalities are reported
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• an unusual double negative T cell population is found in the lymph nodes of these mice
• these double negative T cells all express GFP
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• peripheral CD4+ T cell numbers are reduced by almost two-thirds compared to controls with less dramatic differences in the thymus
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• single positive CD8+ T cell numbers are increased in the thymus and lymph nodes
• some CD8+ T cells express GFP
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• an unusual double negative T cell population is found in the lymph nodes of these mice
• these double negative T cells all express GFP
|
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• peripheral CD4+ T cell numbers are reduced by almost two-thirds compared to controls with less dramatic differences in the thymus
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• single positive CD8+ T cell numbers are increased in the thymus and lymph nodes
• some CD8+ T cells express GFP
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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