About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cidectm1Maka
targeted mutation 1, Masato Kasuga
MGI:3815158
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cidectm1Maka/Cidectm1Maka B6.129P2-Cidectm1Maka MGI:3815175


Genotype
MGI:3815175
hm1
Allelic
Composition
Cidectm1Maka/Cidectm1Maka
Genetic
Background
B6.129P2-Cidectm1Maka
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cidectm1Maka mutation (0 available); any Cidec mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• compared to wild-type mice when fed a standard or high fat diet
• compared to wild-type mice when fed a high fat diet
• compared to wild-type mice when fed a standard or high fat diet
• when fed a high fat diet mice weigh less than wild-type mice
• compared to wild-type mice when fed a standard or high fat diet
• when fed a high fat diet, mice exhibit an increased respiratory quotient compared to wild-type mice
• when fed a standard or high fat diet, mice exhibit improved glucose tolerance compared to similarly treated wild-type mice
• basal rates of lipolysis are increased compared to in wild-type adipocytes

adipose tissue
• brown adipocyte fat droplets are larger than in wild-type mice
• epididymal adipose tissue is brown in color unlike in wild-type mice
• subcutaneous and epididymal white adipocytes exhibit multilocular fat droplets that are smaller than in wild-type mice
• white adipocytes have twice as many mitochondria per cell as in wild-type mice
• epididymal and subcutaneous white adipose tissue are less than in wild-type mice
• when fed a high fat diet, mice did not exhibit as much of an increase in adipose tissue as wild-type mice

growth/size/body
• at 16 weeks, mice weigh less than wild-type mice
• when fed a high fat diet mice weigh less than wild-type mice

liver/biliary system
• compared to wild-type mice when fed a high fat diet

integument





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory