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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adgre5tm1.1Joha
targeted mutation 1.1, Jorg Hamann
MGI:3814838
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adgre5tm1.1Joha/Adgre5tm1.1Joha involves: 129P2/OlaHsd * C57BL/6J * FVB/N MGI:3814845


Genotype
MGI:3814845
hm1
Allelic
Composition		 Adgre5tm1.1Joha/Adgre5tm1.1Joha
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgre5tm1.1Joha mutation (0 available); any Adgre5 mutation (64 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:140713 )
N
• despite CD97 antibodies affecting leukocyte trafficking, mice exhibit normal leukocyte physiology
increased granulocyte number ( J:140713 )
• 40% of mice exhibit an increase in the percentage of circulating granulocytes and an increase in the number of granulocytes in the spleen compared to wild-type mice

hematopoietic system
increased granulocyte number ( J:140713 )
• 40% of mice exhibit an increase in the percentage of circulating granulocytes and an increase in the number of granulocytes in the spleen compared to wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory