Phenotypes associated with this allele

• Allele Symbol: Paxip1^L5Jcs36
• Allele Name: lethal 5 John C Schimenti 36
• Allele ID: MGI:3814327
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Paxip1^L5Jcs36/Paxip1^L5Jcs36	involves: C57BL/6	MGI:3814335

Genotype
MGI:3814335

hm1

• Allelic Composition: Paxip1^L5Jcs36/Paxip1^L5Jcs36
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:140559 )

• embryonic lethality occurs at E10.5

embryonic lethality between implantation and somite formation, complete penetrance ( J:100332 )

• embryonic lethality occurs during E5.5-E7.5

growth/size/body

embryonic growth retardation ( J:140559 )

• E9.5 embryos are severely growth retarded with shortened trunks and poorly developed headfolds

decreased embryo size ( J:140559 )

• E9.5 embryos have shortened trunks

embryo

incomplete embryo turning ( J:140559 )

• E9.5 embryos fail to complete embryonic turning

caudal body truncation ( J:140559 )

• occurs in E9.5 embryos

embryonic growth retardation ( J:140559 )

• E9.5 embryos are severely growth retarded with shortened trunks and poorly developed headfolds

decreased embryo size ( J:140559 )

• E9.5 embryos have shortened trunks

abnormal allantois morphology ( J:140559 )

failure of chorioallantoic fusion ( J:140559 )

• all mutants have a failure of chorioallantoic fusion due to an abnormal allantois

cardiovascular system

absent organized vascular network ( J:140559 )

• E9.5 embryos had a deficiency of blood vessels throughout their bodies

failure of heart looping ( J:140559 )

• E9.5 embryos fail to complete heart looping

integument

pallor ( J:140559 )

• at E10.5, mutant embryos have a pale color, are disorganized, and appear to be degenerating