Phenotypes associated with this allele

• Allele Symbol: Rnf112^{tm1(KOMP)Vlcg}
• Allele Name: targeted mutation 1, Velocigene
• Allele ID: MGI:3812654
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf112^tm1(KOMP)Vlcg/Rnf112^tm1(KOMP)Vlcg	involves: C57BL/6NTac	MGI:5796004

Genotype
MGI:5796004

hm1

• Allelic Composition: Rnf112^{tm1(KOMP)Vlcg}/Rnf112^{tm1(KOMP)Vlcg}
• Genetic Background: involves: C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal reproductive system physiology ( J:232515 )

• some breeding inconsistency

nervous system

decreased brain size ( J:232515 )

• in some mice

decreased dendritic spine number ( J:232515 )

• fewer dendritic spines in vivo

abnormal miniature excitatory postsynaptic currents ( J:232515 )

• decreased frequency

• however, amplitude and mini decay are normal

decreased paired-pulse facilitation ( J:232515 )