All Phenotypes Scn8a<M1Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Scn8a^M1Btlr
mutation 1, Bruce Beutler
MGI:3809770

Summary

2 genotypes

Allelic Composition	Scn8a^M1Btlr/Scn8a^M1Btlr
Genetic Background	C57BL/6J-Scn8a^M1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^M1Btlr mutation (0 available); any Scn8a mutation (100 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

tremors ( J:139714 )

• mice homozygous for this mutation exhibit tremors of variable intensity

abnormal gait ( J:139714 )

• homozygous mutant mice exhibit gait disturbances of variable severity

Allelic Composition	Scn8a^M1Btlr/Scn8a⁺
Genetic Background	C57BL/6J-Scn8a^M1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^M1Btlr mutation (0 available); any Scn8a mutation (100 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

tremors ( J:139714 )

• mice heterozygous for this mutation sometimes exhibit a mild tremor, which does not persist

abnormal gait ( J:139714 )

• heterozygous mutant mice sometimes exhibit a mild gait disturbance, which does not persist

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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