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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze
targeted mutation 6, Hongkui Zeng
MGI:3809522
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+ involves: 129S6/SvEvTac * C57BL/6NCr MGI:4436850
cn2
Chd7tm1.1Dmm/Chd7tm1.1Dmm
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+
Tg(Atoh1-cre)1Bfri/0
involves: 129 * C57BL/6 * C57BL/6NCrl * CBA MGI:7518647
cn3
Chd7tm1.1Dmm/Chd7tm1.1Dmm
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/SvlmJ * 129S6/SvEvTac * C57BL/6J * SJL/J MGI:7518701
cn4
Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+
Tg(Neurog1-cre)1Jejo/0
involves: 129S * C57BL/6 * SJL/J MGI:7518675


Genotype
MGI:4436850
ht1
Allelic
Composition
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6NCr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze mutation (1 available); any Gt(ROSA)26Sor mutation (944 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice are viable and fertile; used for cre reporter expression analysis




Genotype
MGI:7518647
cn2
Allelic
Composition
Chd7tm1.1Dmm/Chd7tm1.1Dmm
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+
Tg(Atoh1-cre)1Bfri/0
Genetic
Background
involves: 129 * C57BL/6 * C57BL/6NCrl * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd7tm1.1Dmm mutation (1 available); any Chd7 mutation (136 available)
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze mutation (1 available); any Gt(ROSA)26Sor mutation (944 available)
Tg(Atoh1-cre)1Bfri mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hearing/vestibular/ear
N
• hair cells are preserved in the apical, mid, and basal cochlear regions




Genotype
MGI:7518701
cn3
Allelic
Composition
Chd7tm1.1Dmm/Chd7tm1.1Dmm
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/Shh+
Genetic
Background
involves: 129S1/SvlmJ * 129S6/SvEvTac * C57BL/6J * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd7tm1.1Dmm mutation (1 available); any Chd7 mutation (136 available)
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze mutation (1 available); any Gt(ROSA)26Sor mutation (944 available)
Shhtm1(EGFP/cre)Cjt mutation (1 available); any Shh mutation (45 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hearing/vestibular/ear
N
• normal hair cells and neurites at P1 in the cochlea




Genotype
MGI:7518675
cn4
Allelic
Composition
Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+
Tg(Neurog1-cre)1Jejo/0
Genetic
Background
involves: 129S * C57BL/6 * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd7Gt(S20-7E1)Sor mutation (1 available); any Chd7 mutation (136 available)
Chd7tm1.1Dmm mutation (1 available); any Chd7 mutation (136 available)
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze mutation (1 available); any Gt(ROSA)26Sor mutation (944 available)
Tg(Neurog1-cre)1Jejo mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• in the apical region of the cochlea aberrant axonal projections that cross, loop, and extend beyond the epithelium are seen
• at P1 total area of the spiral ganglion is reduced





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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory