Phenotypes associated with this allele

• Allele Symbol: Mogs^{tm1(KOMP)Vlcg}
• Allele Name: targeted mutation 1, Velocigene
• Allele ID: MGI:3808372
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mogs^tm1(KOMP)Vlcg/Mogs^tm1(KOMP)Vlcg	C57BL/6N-Mogs^tm1(KOMP)Vlcg/Bay	MGI:5757373
ht2	Mogs^tm1(KOMP)Vlcg/Mogs^+	C57BL/6N-Mogs^tm1(KOMP)Vlcg/Bay	MGI:5797660

Genotype
MGI:5757373

hm1

• Allelic Composition: Mogs^{tm1(KOMP)Vlcg}/Mogs^{tm1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Mogs^{tm1(KOMP)Vlcg}/Bay
• Cell Lines: 10584B-F8

Data Sources

IMPC Data for Mogs

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5797660

ht2

• Allelic Composition: Mogs^{tm1(KOMP)Vlcg}/Mogs⁺
• Genetic Background: C57BL/6N-Mogs^{tm1(KOMP)Vlcg}/Bay
• Cell Lines: 10584B-F8

Data Sources

IMPC Data for Mogs

digestive/alimentary system

abnormal esophagus morphology ( J:211773 )

♂

IMPC - BCM

endocrine/exocrine glands

absent adrenal gland ( J:211773 )

♀

IMPC - BCM

enlarged thymus ( J:211773 )

♂

IMPC - BCM

abnormal thyroid gland morphology ( J:211773 )

IMPC - BCM

abnormal pancreas morphology ( J:211773 )

IMPC - BCM

hematopoietic system

enlarged thymus ( J:211773 )

♂

IMPC - BCM

immune system

enlarged thymus ( J:211773 )

♂

IMPC - BCM

absent lymph nodes ( J:211773 )

IMPC - BCM

limbs/digits/tail

brachydactyly ( J:211773 )

♂

IMPC - BCM

respiratory system

abnormal trachea morphology ( J:211773 )

IMPC - BCM

skeleton

decreased bone mineral density ( J:211773 )

IMPC - BCM

vision/eye

anophthalmia ( J:211773 )

IMPC - BCM