Phenotypes associated with this allele

• Allele Symbol: Atp8a2^agil-2J
• Allele Name: agitans-like 2 Jackson
• Allele ID: MGI:3805719
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atp8a2^agil-2J/Atp8a2^agil-2J	AKR/J-Atp8a2^agil-2J/J	MGI:3814185

Genotype
MGI:3814185

hm1

• Allelic Composition: Atp8a2^agil-2J/Atp8a2^agil-2J
• Genetic Background: AKR/J-Atp8a2^agil-2J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

limb grasping ( J:140624 )

• when picked up by the tail homozygotes pull their back legs in toward their bodies

abnormal gait ( J:140624 )

• wobbling gait recognized at 2 weeks of age

nervous system

brain vacuoles ( J:140624 )

• two mutant males at three weeks of age show vacuoles in the spinal cord white matter, peduncles, and eighth cranial nerve root

abnormal spinal cord white matter morphology ( J:140624 )

• two mutant males at three weeks of age show vacuoles in the spinal cord white matter, peduncles, and eighth cranial nerve root

axonal dystrophy ( J:140624 )

• at three weeks of age dystrophic axons are found in the spinal cord and brain stem

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:140624 )

N • ABR is normal at one month of age

vision/eye

vision/eye phenotype ( J:140624 )

N • normal ophthalmoscopic examination at 1 month of age