Phenotypes associated with this allele

• Allele Symbol: Sostdc1^tm1Noit
• Allele Name: targeted mutation 1, Nobue Itasaki
• Allele ID: MGI:3802970
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sostdc1^tm1Noit/Sostdc1^tm1Noit	involves: C57BL/6 * CBA	MGI:3803318

Genotype
MGI:3803318

hm1

• Allelic Composition: Sostdc1^tm1Noit/Sostdc1^tm1Noit
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:137689 )

• some lethality immediately after birth

• most homozygotes are viable and overtly normal

nervous system

abnormal trigeminal ganglion morphology ( J:137689 )

• the opthalmic lobe of the trigeminal ganglion is poorly attached or not attached at all to the hind brain at E10.5

• phenotype only present in about 50% of homozygotes