All Phenotypes Dclre1c<tm1.1Jpdv> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dclre1c^tm1.1Jpdv
targeted mutation 1.1, Jean-Pierre de Villartay
MGI:3802969

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dclre1c^tm1.1Jpdv/Dclre1c^tm1.1Jpdv	involves: 129P1/ReJ	MGI:3803490

Allelic Composition	Dclre1c^tm1.1Jpdv/Dclre1c^tm1.1Jpdv
Genetic Background	involves: 129P1/ReJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dclre1c^tm1.1Jpdv mutation (1 available); any Dclre1c mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal B cell differentiation ( J:137743 )

• B cell differentiation is arrested

abnormal T cell receptor V(D)J recombination ( J:194422 )

• no recombination is detected in double negative thymocytes

arrested T cell differentiation ( J:137712 )

• thymocyte development is arrested at the immature double negative stage

hematopoietic system