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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Camk2a-Crem)IIEndo
transgene insertion II, Shogo Endo
MGI:3802597
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Camk2a-Crem)IIEndo/0 C57BL/6-Tg(Camk2a-Crem)IIEndo/EndoRbrc MGI:3803754


Genotype
MGI:3803754
tg1
Allelic
Composition
Tg(Camk2a-Crem)IIEndo/0
Genetic
Background
C57BL/6-Tg(Camk2a-Crem)IIEndo/EndoRbrc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Camk2a-Crem)IIEndo mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• despite altered conditioning memory, mice exhibit normal odor discrimination memory
• mice display an attenuated freezing response 24 hours after conditioning compared to wild-type mice
• however, short-term conditioning is normal
• mice exhibit a decreased startle value compared to wild-type mice
• mice exhibit an increased threshold to startle following electric shock compared to wild-type mice
• however, short-term conditioning is normal
• mice take longer to develop more profound seizures and fewer mice reach full kindling compared to similarly treated wild-type mice
• however, afterdischarge duration during kindling is normal

nervous system
• mice take longer to develop more profound seizures and fewer mice reach full kindling compared to similarly treated wild-type mice
• however, afterdischarge duration during kindling is normal

growth/size/body





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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory